Cathepsin D anticorps (Cleaved-Gly65)

N° du produit ABIN1536109

L’anticorps anti-Cathepsin D Polyclonal Lapin est utilisé pour la détection de Cathepsin D dans des échantillons de Humain et Singe. Il a été validé pour WB et ELISA.

Aperçu rapide pour Cathepsin D anticorps (Cleaved-Gly65) (ABIN1536109)

Antigène: Cathepsin D (CTSD)

Reactivité: Humain, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin D est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Cathepsin D anticorps

Épitope: AA 46-95, Cleaved-Gly65

Fonction: Cleaved-Cathepsin D LC (G65) Antibody

Specificité: Cleaved-Cathepsin D LC (G65) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin D LC protein resulting from cleavage adjacent to G65.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human CATD. AA range:46-95

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Cathepsin D

Antigène: Cathepsin D (CTSD)

Autre désignation: CATD

Sujet:

Synonyms: CTSD; CPSD; Cathepsin D

Background: This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015],

Gene Name: CTSD

Protein Name: Cathepsin D

Poids moléculaire: 17 kDa

ID gène: 1509

OMIM: 116840

UniProt: P07339

Pathways: Peptide Hormone Metabolism