Cathepsin L2 anticorps (Cleaved-Leu114)
Aperçu rapide pour Cathepsin L2 anticorps (Cleaved-Leu114) (ABIN1536113)
Antigène
Voir toutes Cathepsin L2 (CTSL2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 95-144, Cleaved-Leu114
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Fonction
- Cleaved-Cathepsin L2 (L114) Antibody
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Specificité
- Cleaved-Cathepsin L2 (L114) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin L2 protein resulting from cleavage adjacent to L114.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human CATL2. AA range:95-144
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- Cathepsin L2 (CTSL2)
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Autre désignation
- CATL2
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Sujet
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Synonyms: CTSL2, CATL2, CTSU, CTSV, Cathepsin L2, Cathepsin U, Cathepsin V
Background: The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2011],
Gene Name: CTSL2
Protein Name: Cathepsin L2
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Poids moléculaire
- 37 kDa
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ID gène
- 1515
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OMIM
- 603308
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UniProt
- O60911
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Pathways
- Toll-Like Receptors Cascades
Antigène
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