CD97 beta anticorps (Cleaved-Ser531)
Aperçu rapide pour CD97 beta anticorps (Cleaved-Ser531) (ABIN1536115)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 512-561, Cleaved-Ser531
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Fonction
- Cleaved-CD97β (S531) Antibody
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Specificité
- Cleaved-CD97β (S531) Polyclonal Antibody detects endogenous levels of fragment of activated CD97β protein resulting from cleavage adjacent to S531.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human CD97 beta. AA range:512-561
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- CD97 beta
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Sujet
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Synonyms: CD97, CD97 antigen, Leukocyte antigen CD97, CD antigen CD97
Background: This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 1
Gene Name: CD97
Protein Name: CD97 antigen
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Poids moléculaire
- 92 and 36 kDa
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ID gène
- 976
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OMIM
- 601211
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UniProt
- P48960
Antigène
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