CD97 beta anticorps (Cleaved-Ser531)

N° du produit ABIN7226090

L’anticorps anti-CD97 beta Polyclonal Lapin est utilisé pour la détection de CD97 beta dans des échantillons de Humain, Souris et Rat. Il a été validé pour ELISA et WB.

Aperçu rapide pour CD97 beta anticorps (Cleaved-Ser531) (ABIN7226090)

Antigène: CD97 beta

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD97 beta est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-CD97 beta anticorps

Épitope: AA 480-560, Cleaved-Ser531

Fonction: Rabbit Anti-Cleaved-CD97β (S531) Polyclonal Antibody

Specificité: Cleaved-CD97β (S531) Polyclonal Antibody detects endogenous levels of fragment of activated CD97β protein resulting from cleavage adjacent to S531.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human CD97beta at AA range: 480-560

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CD97 beta

Antigène: CD97 beta

Autre désignation: CD97beta

Sujet: CD97, CD97 antigen, Leukocyte antigen CD97, CD antigen CD97ADGRE5 (adhesion G protein-coupled receptor E5) encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of ADGRE5 may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for ADGRE5. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.

Poids moléculaire: 34kD

ID gène: 976

UniProt: P48960