MRPL41 anticorps (C-Term)

N° du produit ABIN1536787

Cet anticorps Lapin Polyclonal détecte spécifiquement MRPL41 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour MRPL41 anticorps (C-Term) (ABIN1536787)

Antigène: MRPL41 (Mitochondrial Ribosomal Protein L41 (MRPL41))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MRPL41 est non-conjugé

Application: Western Blotting (WB)

Clone: RB30609

Détail du produit anti-MRPL41 anticorps

Épitope: AA 174-203, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PIG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-203 amino acids from the C-terminal region of human PIG3.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: PIG3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur MRPL41

Antigène: MRPL41 (Mitochondrial Ribosomal Protein L41 (MRPL41))

Autre désignation: PIG3

Sujet: The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene.

Poids moléculaire: 35536

ID gène: 9540

NCBI Accession: NP_001193731, NP_004872, NP_671713

UniProt: Q53FA7

Pathways: Signalisation p53