IL5RA anticorps (C-Term)

N° du produit ABIN1537258

Cet anticorps Lapin Polyclonal détecte spécifiquement IL5RA dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour IL5RA anticorps (C-Term) (ABIN1537258)

Antigène: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL5RA est non-conjugé

Application: Western Blotting (WB)

Clone: RB40195

Détail du produit anti-IL5RA anticorps

Épitope: AA 391-420, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This IL5RA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-420 amino acids from the C-terminal region of human IL5RA.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: IL5RA Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur IL5RA

Antigène: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Autre désignation: IL5RA

Sujet: The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported.

Poids moléculaire: 47685

ID gène: 3568

NCBI Accession: NP_000555, NP_001230028, NP_783851, NP_783852, NP_783853, NP_783854, NP_783855

UniProt: Q01344

Pathways: Signalistation JAK/STAT