Fibulin 5 anticorps (C-Term)

N° du produit ABIN1537265

L’anticorps anti-Fibulin 5 Polyclonal Lapin est utilisé pour la détection de Fibulin 5 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour Fibulin 5 anticorps (C-Term) (ABIN1537265)

Antigène: Fibulin 5 (FBLN5)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Fibulin 5 est non-conjugé

Application: Western Blotting (WB)

Clone: RB23905

Détail du produit anti-Fibulin 5 anticorps

Épitope: AA 393-421, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This FBLN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 393-421 amino acids from the C-terminal region of human FBLN5.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: FBLN5 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur Fibulin 5

Antigène: Fibulin 5 (FBLN5)

Autre désignation: FBLN5

Sujet: The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).

Poids moléculaire: 50180

ID gène: 10516

NCBI Accession: NP_006320

UniProt: Q9UBX5

Pathways: SARS-CoV-2 Protein Interactome