PRICKLE1 anticorps (C-Term)

N° du produit ABIN1537540

Cet anticorps Lapin Polyclonal détecte spécifiquement PRICKLE1 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour PRICKLE1 anticorps (C-Term) (ABIN1537540)

Antigène: PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRICKLE1 est non-conjugé

Application: Western Blotting (WB)

Clone: RB39636

Détail du produit anti-PRICKLE1 anticorps

Épitope: AA 678-704, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PRICKLE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 678-704 amino acids from the C-terminal region of human PRICKLE1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: PRICKLE1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur PRICKLE1

Antigène: PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))

Autre désignation: PRICKLE1

Sujet: This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3.

Poids moléculaire: 94300

ID gène: 144165

NCBI Accession: NP_001138353, NP_001138354, NP_001138355, NP_694571

UniProt: Q96MT3

Pathways: Signalisation WNT, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development, Protein targeting to Nucleus