AKAP5 anticorps (AA 115-143)

N° du produit ABIN1537769

L’anticorps anti-AKAP5 Polyclonal Lapin est utilisé pour la détection de AKAP5 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour AKAP5 anticorps (AA 115-143) (ABIN1537769)

Antigène: AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKAP5 est non-conjugé

Application: Western Blotting (WB)

Clone: RB39500

Détail du produit anti-AKAP5 anticorps

Épitope: AA 115-143

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This AKAP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-143 amino acids from the Central region of human AKAP5.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: AKAP5 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur AKAP5

Antigène: AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))

Autre désignation: AKAP5

Sujet: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.

Poids moléculaire: 47088

ID gène: 9495

NCBI Accession: NP_004848

UniProt: P24588

Pathways: cAMP Metabolic Process