AKAP5 anticorps (AA 1-80)

N° du produit ABIN7213526

Cet anticorps Lapin Polyclonal détecte spécifiquement AKAP5 dans WB, ELISA, IHC et IF. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour AKAP5 anticorps (AA 1-80) (ABIN7213526)

Antigène: AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKAP5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-AKAP5 anticorps

Épitope: AA 1-80

Fonction: Rabbit Anti-AKAP 79 Polyclonal Antibody

Specificité: AKAP 79 Polyclonal Antibody detects endogenous levels of AKAP 79 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the N-terminal region of human AKAP 79 at AA range: 1-80

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur AKAP5

Antigène: AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))

Autre désignation: AKAP 79

Sujet: AKAP5, AKAP79, A-kinase anchor protein 5, AKAP-5, A-kinase anchor protein 79 kDa, AKAP 79, H21, cAMP-dependent protein kinase regulatory subunit II high affinity-binding proteinThe A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP5 encodes a member of the AKAP family. The encoded protein (A-kinase anchoring protein 5) binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.

Poids moléculaire: 47kD

ID gène: 9495

UniProt: P24588

Pathways: cAMP Metabolic Process