RRM2B anticorps (AA 128-157)

N° du produit ABIN1537814

L’anticorps anti-RRM2B Polyclonal Lapin est utilisé pour la détection de RRM2B dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour RRM2B anticorps (AA 128-157) (ABIN1537814)

Antigène: RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RRM2B est non-conjugé

Application: Western Blotting (WB)

Clone: RB36901

Détail du produit anti-RRM2B anticorps

Épitope: AA 128-157

Homologie: Pr, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RRM2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-157 amino acids from the Central region of human RRM2B.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: RRM2B Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur RRM2B

Antigène: RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))

Autre désignation: RRM2B

Sujet: This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.

Poids moléculaire: 40737

ID gène: 50484

NCBI Accession: NP_001165948, NP_001165949, NP_056528

UniProt: Q7LG56

Pathways: Signalisation p53, Negative Regulation of intrinsic apoptotic Signaling