DUSP12 anticorps (AA 162-191)

N° du produit ABIN1537912

Cet anticorps Lapin Polyclonal détecte spécifiquement DUSP12 dans WB. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour DUSP12 anticorps (AA 162-191) (ABIN1537912)

Antigène: DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP12 est non-conjugé

Application: Western Blotting (WB)

Clone: RB35761

Détail du produit anti-DUSP12 anticorps

Épitope: AA 162-191

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This DUSP12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-191 amino acids from the Central region of human DUSP12.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: DUSP12 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur DUSP12

Antigène: DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))

Autre désignation: DUSP12

Sujet: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.

Poids moléculaire: 37687

ID gène: 11266

NCBI Accession: NP_009171

UniProt: Q9UNI6

Pathways: Regulation of Carbohydrate Metabolic Process