TIGAR anticorps (N-Term)
Aperçu rapide pour TIGAR anticorps (N-Term) (ABIN1538901)
Antigène
Voir toutes TIGAR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-30, N-Term
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This TIGAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TIGAR.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- TIGAR Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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Date de péremption
- 6 months
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- TIGAR (TP53 induced glycolysis regulatory phosphatase (TIGAR))
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Autre désignation
- TIGAR
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Sujet
- This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region. [provided by RefSeq].
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Poids moléculaire
- 30063
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ID gène
- 57103
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NCBI Accession
- NP_065108
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UniProt
- Q9NQ88
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Pathways
- L'effet Warburg
Antigène
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