GSTM1 anticorps (AA 184-211)

N° du produit ABIN1539938

L’anticorps anti-GSTM1 Monoclonal Souris est utilisé pour la détection de GSTM1 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour GSTM1 anticorps (AA 184-211) (ABIN1539938)

Antigène: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GSTM1 est non-conjugé

Application: Western Blotting (WB)

Clone: 524CT17-2-5

Détail du produit anti-GSTM1 anticorps

Épitope: AA 184-211

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogène: This GSTM1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 184-211 amino acids from human GSTM1.

Isotype: IgM

Information d'application

Indications d'application: WB: 1:500~2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: GSTM1 Antibody(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur GSTM1

Antigène: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Autre désignation: GSTM1

Sujet: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.

Poids moléculaire: 25712

ID gène: 2944

NCBI Accession: NP_000552, NP_666533

UniProt: P09488

Pathways: Negative Regulation of Transporter Activity