Syndecan 1 anticorps (C-Term)

N° du produit ABIN1539995

L’anticorps Souris Monoclonal anti-Syndecan 1 a été validé pour WB, FACS et IF. Il convient pour détecter Syndecan 1 dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour Syndecan 1 anticorps (C-Term) (ABIN1539995)

Antigène: Syndecan 1 (SDC1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Syndecan 1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 587CT7-3-6-5

Détail du produit anti-Syndecan 1 anticorps

Épitope: AA 210-238, C-Term

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogène: This CD138 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 210-238 amino acids from the C-terminal region of human CD138.

Isotype: IgM

Information d'application

Indications d'application: IF: 1:10~50. IF: 1:10~50. IF: 1:10~50. WB: 1:500~8000. FC: 1:10~50. FC: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: CD138 Antibody (C-term)(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Références pour anticorps anti-Syndecan 1 (ABIN1539995)

Chen, Zou, Zong, Meng, An, Yang: "Anti-human CD138 monoclonal antibodies and their bispecific formats: generation and characterization." dans: Immunopharmacology and immunotoxicology, Vol. 38, Issue 3, pp. 175-83, (2017) (PubMed).

Détails sur Syndecan 1

Antigène: Syndecan 1 (SDC1)

Autre désignation: CD138

Sujet: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

Poids moléculaire: 32462

ID gène: 6382

NCBI Accession: NP_001006947, NP_002988

UniProt: P18827

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism