HMOX1 anticorps (N-Term)

N° du produit ABIN155124

Détail du produit anti-HMOX1 anticorps

Antigène: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Hamster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HMOX1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: The antibody recognizes ~32 kDa Heme-Oxygenase-1.

Purification: Affinity Chromatography

Immunogène: Synthetic peptide surrounding amino acid near the N-terminus of Human HO-1

Information d'application

Indications d'application: Western Blot: 0.5-2 μg/mL. Immunoprecipitation: 10-20 μg/mL. Immunohistochemistry: 10-20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS, 0.5 % BSA, 30 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C/-80 °C

Stockage commentaire: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Détails sur HMOX1

Antigène: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Autre désignation: Heme Oxygenase 1 / HMOX1 (HMOX1 Produits)

Synonymes: anticorps HMOX1, anticorps ARABIDOPSIS THALIANA HEME OXYGENASE 1, anticorps ATHO1, anticorps F18A8.4, anticorps F18A8_4, anticorps GENOMES UNCOUPLED 2, anticorps GUN2, anticorps HEME OXYGENASE, anticorps HEME OXYGENASE 1, anticorps HEME OXYGENASE 6, anticorps HO1, anticorps HY1, anticorps HY6, anticorps PLASTID HEME OXYGENASE, anticorps REVERSAL OF THE DET PHENOTYPE 4, anticorps HO-1, anticorps wu:fc27c04, anticorps zgc:65984, anticorps D8Wsu38e, anticorps Hemox, anticorps Hmox, anticorps Hsp32, anticorps HEOXG, anticorps Heox, anticorps Ho-1, anticorps Ho1, anticorps hsp32, anticorps MGC132176, anticorps Hmox1, anticorps HMOX1D, anticorps HSP32, anticorps bK286B10, anticorps heme oxygenase 1, anticorps Plant heme oxygenase (decyclizing) family protein, anticorps Heme oxygenase, anticorps heme oxygenase, anticorps heme oxygenase 1, chloroplastic, anticorps heme oxygenase 1a, anticorps heme oxygenase 1 L homeolog, anticorps HMOX1, anticorps TED4, anticorps ho1, anticorps P9301_RS17555, anticorps A9601_RS17590, anticorps MAE_RS06565, anticorps HO1, anticorps hmox1a, anticorps CPE0214, anticorps Cyan7425_2962, anticorps Hmox1, anticorps hmox1.L, anticorps AM1_C0205, anticorps CC1G_11686, anticorps CpipJ_CPIJ007246

Sujet: Heme oxygenase-1 (HO-1) or HSP32 is the inducible isoform of heme oxygenase which catalyzes the NADPH, O2 and cytochrome P450 reductase dependent oxidation of heme to carbon monoxide, iron and biliverdin that is immediately reduced to bilirubin. To date, three heme oxygenase isoforms HO-1, HO-2 and HO-3 have been identified. HO-1, also known as Hsp32, a major heat shock/stress response protein, is ubiquitous and its mRNA as well as its activity can be increased several-fold by heme, other metalloporphyrins, transition metals and stimuli that induce cellular stress. The 5'-untranslated region (UTR) of HO-1 has several consensus regulatory elements that include sites for activator protein 1 (AP-1), metal responsive element (MRE), oncogene c-myc/max heterodimer binding site (Myc/Max), antioxidant response element (ARE) and GC box binding (Sp1). HO-1 expression has been shown to increase in benign postatic hyperplasia (BPH) and malignant prostate tissue suggesting a role for this stress protein in the pathogenesis of BPH and prostate cancer.Synonyms: HO, HO-1, HO1

ID gène: 3162

NCBI Accession: NP_002124

UniProt: P09601

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome