TEK anticorps (Extracellular Domain) (Biotin)

N° du produit ABIN155163

Cet anticorps anti-TEK est un anticorps Souris Monoclonal détectant TEK dans WB, FACS et EIA. Adapté pour Humain.

Aperçu rapide pour TEK anticorps (Extracellular Domain) (Biotin) (ABIN155163)

Antigène: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TEK est conjugé à/à la Biotin

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Clone: Cl-2

Détail du produit anti-TEK anticorps (Biotin)

Épitope: Extracellular Domain

Specificité: The unconjugated Monoclonal antibody will detect native Human TIE-2/tek in ELISA experiments and on the surface of different Human cell types.

Purification: Protein G Chromatography

Immunogène: Recombinant Human soluble extracellular domain of TIE-2

Isotype: IgG1

Information d'application

Indications d'application: FACS analysis and cell sorting: 2-5 μg/mL. ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore to a concentration of 50 μg/mL with sterile PBS solution containing 0.1 % BSA.

Buffer: 0.1 M Tris-Cl, 0.1 M NaCl, pH 7.4, 0.02 % Sodium Azide, 50x BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: This product is photosensitive and should be protected from light

Stock: 4 °C

Stockage commentaire: Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Détails sur TEK

Antigène: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Autre désignation: CD202b / TEK

Sujet: TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin like loops separated by three epidermal growth factor like repeats that are connected to three fibronectin type III like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations, the TIE2 signaling pathway appears to be critical for endothelial cell smooth muscle cell communication in venous morphogenesis.Synonyms: Angiopoietin-1 receptor, TIE-2, TIE2, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, p140 TEK

ID gène: 7010

NCBI Accession: NP_000450

UniProt: Q02763

Pathways: Signalisation RTK, Growth Factor Binding