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VEGFC anticorps

VEGFC Reactivité: Rat WB, ELISA, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1589911
  • Antigène Voir toutes VEGFC Anticorps
    VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
    Reactivité
    • 97
    • 57
    • 38
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Rat
    Hôte
    • 93
    • 29
    • 1
    • 1
    • 1
    Lapin
    Clonalité
    • 98
    • 27
    Polyclonal
    Conjugué
    • 49
    • 17
    • 15
    • 8
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp VEGFC est non-conjugé
    Application
    • 115
    • 55
    • 47
    • 26
    • 26
    • 25
    • 14
    • 10
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    Specificité
    Recombinant rat VEGF-C
    Attributs du produit
    Chromosomal location: 16p11
    Produced from sera of rabbits immunized with highly pure recombinant rat dNdC-VEGF-C.
    Purification
    Anti-rat VEGF-C IgG was purified by affinity chromatography with immobilized Protein A.
    Isotype
    IgG
    Top Product
    Discover our top product VEGFC Anticorps primaire
  • Indications d'application
    Western Blot: use 2-5 µg/mL
    Commentaires

    Rabbit IG Polyclonal Antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
    Buffer
    PBS
    Conseil sur la manipulation
    Centrifuge vial prior to opening.
    Stock
    -20 °C
    Stockage commentaire
    The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.
    Date de péremption
    6 months
  • Maertens, Erpicum, Detry, Blacher, Lenoir, Carnet, Péqueux, Cataldo, Lecomte, Paupert, Noel: "Bone marrow-derived mesenchymal stem cells drive lymphangiogenesis." dans: PLoS ONE, Vol. 9, Issue 9, pp. e106976, (2014) (PubMed).

  • Antigène
    VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
    Autre désignation
    VEGF-C (VEGFC Produits)
    Synonymes
    anticorps VEGFC, anticorps vegf-c, anticorps xvegf-c, anticorps Flt4-L, anticorps VRP, anticorps AW228853, anticorps VEGF-C, anticorps vascular endothelial growth factor c, anticorps vascular endothelial growth factor C, anticorps vascular endothelial growth factor C S homeolog, anticorps vegfc, anticorps VEGFC, anticorps vegfc.S, anticorps Vegfc
    Sujet
    VEGF-C, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-C is expressed in various tissues, but is not produced in peripheral blood lymphocytes. It forms cell surfaced-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-C may play a role in the formation of the venous and lymphatic vascular systems. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis. Recombinant, fully processed rat VEGF-C is a 16-18 kDa non-disulfide linked homodimeric protein consisting of two 116 amino acid polypeptide chains. Due to glycosylation the protein migrates as a 20.0-22.0 kDa band under non-reducing condition.
    Synonyms: vascular endothelial growth factor C, Vegfc
    NCBI Accession
    NP_446105, NM_053653
    UniProt
    O35757
    Pathways
    Signalisation RTK, Signaling Events mediated by VEGFR1 and VEGFR2
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