LYVE1 anticorps
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- Antigène Voir toutes LYVE1 Anticorps
- LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp LYVE1 est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- Recombinant mouse soluble Lyve-1
- Attributs du produit
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Chromosomal location: 7, 7F2
Produced from sera of rabbits immunized with highly pure recombinant mouse soluble LYVE-1 produced in insect cells. The recombinant soluble LYVE-1 consists of amino acid 24 (Ala) to 228 (Gly) and is fused to a C-terminal His-tag (6xHis). - Isotype
- IgG
- Top Product
- Discover our top product LYVE1 Anticorps primaire
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- Indications d'application
- Western Blot: use 2-5 µg/mL, FACS: use 3-10 µg/mL, IF/IHC: applicable with cryo-sections.
- Commentaires
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Rabbit IG Polyclonal Antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
- Buffer
- PBS
- Conseil sur la manipulation
- Centrifuge vial prior to opening.
- Stock
- -20 °C
- Stockage commentaire
- The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.
- Date de péremption
- 6 months
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The lymphatic vascular system of the mouse head." dans: Cell and tissue research, (2016) (PubMed).
: "Medicinal facilities to B16F10 melanoma cells for distant metastasis control with a supramolecular complex by DEAE-dextran-MMA copolymer/paclitaxel." dans: Drug delivery and translational research, Vol. 5, Issue 1, pp. 38-50, (2015) (PubMed).
: "TGF-?1-induced EMT promotes targeted migration of breast cancer cells through the lymphatic system by the activation of CCR7/CCL21-mediated chemotaxis." dans: Oncogene, (2015) (PubMed).
: "Endothelial, but not smooth muscle, peroxisome proliferator-activated receptor ?/? regulates vascular permeability and anaphylaxis." dans: The Journal of allergy and clinical immunology, Vol. 135, Issue 6, pp. 1625-35.e5, (2015) (PubMed).
: "Arterial wall lymphangiogenesis is increased in the human iliac atherosclerotic arteries: involvement of CCR7 receptor." dans: Lymphatic research and biology, Vol. 12, Issue 4, pp. 222-31, (2014) (PubMed).
: "Inhibition of VEGFR-3 activation in tumor-draining lymph nodes suppresses the outgrowth of lymph node metastases in the MT-450 syngeneic rat breast cancer model." dans: Clinical & experimental metastasis, Vol. 31, Issue 3, pp. 351-65, (2014) (PubMed).
: "The effect of podoplanin inhibition on lymphangiogenesis under pathological conditions." dans: Investigative ophthalmology & visual science, Vol. 55, Issue 8, pp. 4813-22, (2014) (PubMed).
: "Cancer-associated fibroblasts expressing CXCL14 rely upon NOS1-derived nitric oxide signaling for their tumor-supporting properties." dans: Cancer research, Vol. 74, Issue 11, pp. 2999-3010, (2014) (PubMed).
: "Rapamycin inhibition of CFA-induced lymphangiogenesis in PLN is independent of mast cells." dans: Molecular biology reports, Vol. 41, Issue 4, pp. 2217-28, (2014) (PubMed).
: "Clonal analysis identifies hemogenic endothelium as the source of the blood-endothelial common lineage in the mouse embryo." dans: Blood, Vol. 124, Issue 16, pp. 2523-32, (2014) (PubMed).
: "Lymphatic drainage pathways from the cervix uteri: implications for radical hysterectomy?" dans: Gynecologic oncology, Vol. 132, Issue 1, pp. 107-13, (2014) (PubMed).
: "Steady-state antigen scavenging, cross-presentation, and CD8+ T cell priming: a new role for lymphatic endothelial cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 11, pp. 5002-11, (2014) (PubMed).
: "Apelin promotes lymphangiogenesis and lymph node metastasis." dans: Oncotarget, Vol. 5, Issue 12, pp. 4426-37, (2014) (PubMed).
: "Tumor-derived interleukin-1 promotes lymphangiogenesis and lymph node metastasis through M2-type macrophages." dans: PLoS ONE, Vol. 9, Issue 6, pp. e99568, (2014) (PubMed).
: "Optimization and regeneration kinetics of lymphatic-specific photodynamic therapy in the mouse dermis." dans: Angiogenesis, Vol. 17, Issue 2, pp. 347-57, (2014) (PubMed).
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The lymphatic vascular system of the mouse head." dans: Cell and tissue research, (2016) (PubMed).
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- Antigène
- LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))
- Autre désignation
- Lyve-1 (LYVE1 Produits)
- Synonymes
- anticorps LYVE1, anticorps XLKD1, anticorps CRSBP-1, anticorps HAR, anticorps LYVE-1, anticorps 1200012G08Rik, anticorps Crsbp-1, anticorps Lyve-1, anticorps Xlkd1, anticorps lymphatic vessel endothelial hyaluronic receptor 1a, anticorps lymphatic vessel endothelial hyaluronan receptor 1, anticorps lyve1a, anticorps LYVE1, anticorps Lyve1
- Sujet
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LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41 % similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
Synonyms: Lyve1, Xlkd1, Lyve-1, Crsbp-1, 1200012G08Rik - NCBI Accession
- NP_444477, NM_053247
- UniProt
- Q8BHC0
- Pathways
- Glycosaminoglycan Metabolic Process
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