LIF anticorps

N° du produit ABIN1589935

Cet anticorps Lapin Polyclonal détecte spécifiquement LIF dans WB. Il présente une réactivité envers Souris.

Aperçu rapide pour LIF anticorps (ABIN1589935)

Antigène: LIF (Leukemia Inhibitory Factor (LIF))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIF est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LIF anticorps

Fonction: LIF antibody

Specificité: Recombinant mouse LIF

Attributs du produit: Chromosomal location: 11 A1-A2, 11 00.25 cM
Produced from sera of rabbits immunized with highly pure recombinant mouse Leukemia Inhibitory Factor (LIF) [Ser24 - Phe203, produced in E. coli].

Purification: Anti-human LIF was purified by affinity chromatography with immobilized Protein A.

Immunogène: Recombinant mouse LIF (ABIN1589657)

Isotype: IgG

Information d'application

Indications d'application: Western Blot: use at 2-5 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS

Conseil sur la manipulation: Centrifuge vial prior to opening.

Stock: 4 °C,-20 °C

Stockage commentaire: The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

Date de péremption: 24 months

Détails sur LIF

Antigène: LIF (Leukemia Inhibitory Factor (LIF))

Autre désignation: LIF

Sujet: Lif,Leukemia Inhibitory Factor also called LIF is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78 % identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF.

ID gène: 16878

NCBI Accession: NM_008501, NP_032527

UniProt: P09056

Pathways: Signalistation JAK/STAT, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Stem Cell Maintenance, Growth Factor Binding