Geminin anticorps (AA 1-209)
Aperçu rapide pour Geminin anticorps (AA 1-209) (ABIN361058)
Antigène
Voir toutes Geminin (GMNN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-209
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Fonction
- Human Geminin antibody
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Purification
- Purified
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Immunogène
- Recombinant human Geminin (1-209 aa) purified from E. coli
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Isotype
- IgG1 kappa
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Indications d'application
- Recommended dilution 1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing cycles
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))
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Autre désignation
- Geminin
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Sujet
- Geminin is a 25 kDa protein, which inhibits DNA replication and is degraded during the mitotic phase of the cell cycle. Geminin controls replication by binding to the licensing factor Cdt1, and is involved in neural differentiation. In addition, geminin directly interacts with Six3 and Hox homeodomain proteins during embryogenesis and inhibits their functions.
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NCBI Accession
- NP_056979
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Pathways
- EGFR Signaling Pathway, DNA Replication
Antigène
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