APC anticorps (AA 2544-2843)

N° du produit ABIN1678690

Cet anticorps anti-APC est un anticorps Lapin Polyclonal détectant APC dans WB et IHC. Adapté pour Humain.

Aperçu rapide pour APC anticorps (AA 2544-2843) (ABIN1678690)

Antigène: APC (Adenomatous Polyposis Coli (APC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APC est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-APC anticorps

Épitope: AA 2544-2843

Séquence: SGTWKREHSK HSSSLPRVST WRRTGSSSSI LSASSESSEK AKSEDEKHVN SISGTKQSKE NQVSAKGTWR KIKENEFSPT NSTSQTVSSG ATNGAESKTL IYQMAPAVSK TEDVWVRIED CPINNPRSGR SPTGNTPPVI DSVSEKANPN IKDSKDNQAK QNVGNGSVPM RTVGLENRLN SFIQVDAPDQ KGTEIKPGQN NPVPVSETNE SSIVERTPFS SSSSSKHSSP SGTVAARVTP FNYNPSPRKS SADSTSARPS QIPTPVNNNT KKRDSKTDST ESSGTQSPKR HSGSYLVTSV

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 2544-2843 of human APC (NP_000029.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur APC

Antigène: APC (Adenomatous Polyposis Coli (APC))

Autre désignation: APC

Sujet: This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.,APC,BTPS2,DP2,DP2.5,DP3,GS,PPP1R46,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Centrosome,Cell Adhesion,Microtubules,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Neuroscience,Cell Type Marker,Stem Cells,Cardiovascular,Heart,Cardiogenesis,Oligodendrocyte marker,APC

Poids moléculaire: 300 kDa/311 kDa

ID gène: 324

UniProt: P25054

Pathways: Signalisation WNT, Stem Cell Maintenance, Cell-Cell Junction Organization