PLAT anticorps

N° du produit ABIN7101650

Détail du produit anti-PLAT anticorps

Antigène: PLAT (Plasminogen Activator, Tissue (PLAT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PLAT est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human tPA/tPA/PLAT

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PLAT

Antigène: PLAT (Plasminogen Activator, Tissue (PLAT))

Autre désignation: PLAT (PLAT Produits)

Synonymes: anticorps T-PA, anticorps TPA, anticorps AU020998, anticorps AW212668, anticorps D8Ertd2e, anticorps tPA, anticorps PATISS, anticorps tpa, anticorps Plat, anticorps plat, anticorps t-pa, anticorps plasminogen activator, tissue type, anticorps plasminogen activator, tissue, anticorps chromosome 20 open reading frame 181, anticorps plasminogen activator, tissue L homeolog, anticorps PLAT, anticorps Plat, anticorps plat, anticorps C20orf181, anticorps plat.L

Sujet: This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016],T-PA, TPA,Blood,Blood_Serum Proteins,Cancer,Cardiovascular,Cell Biology & Developmental Biology,Endocrine & Metabolism,Hypoxia,Ubiquitin,PLAT

Poids moléculaire: 63 kDa

ID gène: 5327

UniProt: P00750

Pathways: Autophagy, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interactome