CTBP2 anticorps (C-Term)

N° du produit ABIN1679396

L’anticorps Lapin Polyclonal anti-CTBP2 a été validé pour WB et IF. Il convient pour détecter CTBP2 dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour CTBP2 anticorps (C-Term) (ABIN1679396)

Antigène: CTBP2 (C-terminal Binding Protein 2 (CTBP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTBP2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-CTBP2 anticorps

Épitope: C-Term

Séquence: SEPFSFAQGP LKDAPNLICT PHTAWYSEQA SLEMREAAAT EIRRAITGRI PESLRNCVNK EFFVTSAPWS VIDQQAIHPE LNGATYRYPP GIVGVAPGGL PAAMEGIIPG GIPVTHNLPT VAHPSQAPSP NQPTKHGDNR EHPNEQ

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human CTBP2 (NP_001320.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-CTBP2 (ABIN1679396)

Li, Liu, He, Yang, Pei, Li, Liu, Chen, Xie, Xu, Ting, Zhang, Jin, Liu, Zhang, Yuan, Yang, Wu, Zhang, Yang, Yi, Liang, Shang, Sun: "ZNF516 suppresses EGFR by targeting the CtBP/LSD1/CoREST complex to chromatin." dans: Nature communications, Vol. 8, Issue 1, pp. 691, (2018) (PubMed).

Détails sur CTBP2

Antigène: CTBP2 (C-terminal Binding Protein 2 (CTBP2))

Autre désignation: CTBP2

Sujet: This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3, however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene.,CTBP2,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Notch Signaling Pathway,Neuroscience,Cell Type Marker,Neuron marker,Synapse marker,CTBP2

Poids moléculaire: 48 kDa/56 kDa/106 kDa

ID gène: 1488

UniProt: P56545