GUCY2D anticorps (AA 52-350)
Aperçu rapide pour GUCY2D anticorps (AA 52-350) (ABIN1680144)
Antigène
Voir toutes GUCY2D AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 52-350
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Séquence
- AVFTVGVLGP WACDPIFSRA RPDLAARLAA ARLNRDPGLA GGPRFEVALL PEPCRTPGSL GAVSSALARV SGLVGPVNPA ACRPAELLAE EAGIALVPWG CPWTQAEGTT APAVTPAADA LYALLRAFGW ARVALVTAPQ DLWVEAGRSL STALRARGLP VASVTSMEPL DLSGAREALR KVRDGPRVTA VIMVMHSVLL GGEEQRYLLE AAEELGLTDG SLVFLPFDTI HYALSPGPEA LAALANSSQL RRAHDAVLTL TRHCPSEGSV LDSLRRAQER RELPSDLNLQ QVSPLFGTI
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 52-350 of human GUCY2D (NP_000171.1).
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Isotype
- IgG
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Indications d'application
- WB,1:200 - 1:2000
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- GUCY2D (Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D))
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Autre désignation
- GUCY2D
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Sujet
- This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.,GUCY2D,CORD5,CORD6,CYGD,GUC1A4,GUC2D,LCA,LCA1,RCD2,RETGC-1,ROS-GC1,ROSGC,retGC,Signal Transduction,Neuroscience,GUCY2D
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Poids moléculaire
- 120 kDa
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ID gène
- 3000
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UniProt
- Q02846
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
Antigène
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