KISS1 anticorps

N° du produit ABIN1680598

Détail du produit anti-KISS1 anticorps

Antigène: KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KISS1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide of human KISS1

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur KISS1

Antigène: KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))

Autre désignation: KISS1 (KISS1 Produits)

Synonymes: anticorps HH13, anticorps KiSS-1, anticorps metastatin, anticorps Eseptin, anticorps KiSS-1 metastasis-suppressor, anticorps KISS1, anticorps kiss1, anticorps Kiss1

Sujet: This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues.,KISS1,HH13,KiSS-1,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Endocrine & Metabolism,Neuroscience,KISS1

Poids moléculaire: 14 kDa

ID gène: 3814

UniProt: Q15726

Pathways: Positive Regulation of Peptide Hormone Secretion