ITGA4 anticorps
Aperçu rapide pour ITGA4 anticorps (ABIN1682337)
Antigène
Voir toutes ITGA4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Réactivité croisée
- Humain, Souris, Rat
-
Attributs du produit
- Monoclonal Antibodies
-
Purification
- Affinity purification
-
Immunogène
- A synthesized peptide derived from human Integrin alpha 4 (ITGA4/CD49d) (ITGA4/CD49d)
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200
-
Restrictions
- For Research Use only
-
-
-
Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- ITGA4 (Integrin alpha 4 (ITGA4))
-
Autre désignation
- ITGA4
-
Sujet
- The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],CD49D, IA4,CDs,Cell Adhesion,Cell Biology & Developmental Biology,Cytoskeleton,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,Immunology & Inflammation,MAPK-Erk Signaling Pathway,Neural Stem Cells,PI3K-Akt Signaling Pathway,Signal Transduction,Stem Cells,ITGA4
-
Poids moléculaire
- 150 kDa
-
ID gène
- 3676
-
UniProt
- P13612
-
Pathways
- Integrin Complex
Antigène
-