TIE1 anticorps (AA 350-600)
Aperçu rapide pour TIE1 anticorps (AA 350-600) (ABIN1683033)
Antigène
Voir toutes TIE1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 350-600
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Séquence
- IPQILNMASE LEFNLETMPR INCAAAGNPF PVRGSIELRK PDGTVLLSTK AIVEPEKTTA EFEVPRLVLA DSGFWECRVS TSGGQDSRRF KVNVKVPPVP LAAPRLLTKQ SRQLVVSPLV SFSGDGPIST VRLHYRPQDS TMDWSTIVVD PSENVTLMNL RPKTGYSVRV QLSRPGEGGE GAWGPPTLMT TDCPEPLLQP WLEGWHVEGT DRLRVSWSLP LVPGPLVGDG FLLRLWDGTR GQERRENVSS P
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Réactivité croisée
- Humain, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 350-600 of human TIE1 (NP_005415.1).
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Isotype
- IgG
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Indications d'application
- WB,1:200 - 1:2000
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
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Autre désignation
- TIE1
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Sujet
- This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,TIE1,JTK14,TIE,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,Stem Cells,Endothelial Progenitors,Cardiovascular,TIE1
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Poids moléculaire
- 34 kDa/40 kDa/125 kDa
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ID gène
- 7075
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UniProt
- P35590
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Pathways
- Signalisation RTK
Antigène
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