PDE8A anticorps

N° du produit ABIN1690735

Cet anticorps Souris Monoclonal détecte spécifiquement PDE8A dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour PDE8A anticorps (ABIN1690735)

Antigène: PDE8A (phosphodiesterase 8A (PDE8A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PDE8A est non-conjugé

Application: Western Blotting (WB)

Clone: EM-52

Détail du produit anti-PDE8A anticorps

Fonction: Anti-PDE8A Purified

Specificité: The mouse monoclonal antibody EM-52 recognizes PDE8a (phosphodiesterase 8 A), an approximately 93 kDa intracellular enzyme that hydrolyzes cAMP to 5'AMP.

Réactivité croisée (Details): Human

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Immunogène: Human PDE8a

Isotype: IgG1 kappa

Information d'application

Indications d'application: Western blotting: Recommended dilution: 1-2 μg/mL.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur PDE8A

Antigène: PDE8A (phosphodiesterase 8A (PDE8A))

Autre désignation: PDE8A

Sujet: Phosphodiesterase 8A,PDE8a (high affinity cAMP-specific and IBMX-insensitive 3´,5´-cyclic phosphodiesterase 8 A) is a cyclic nucleotide phosphodiesterase, which hydrolyzes cAMP, an important regulator and mediator of multiple cellular responses to extracellular signals. It is expressed in a wide variety of tissues including testis, ovary, small intestine, and colon. It is not expressed e.g. in thymus. PDE8a is composed of C-terminal catalytic domain containing two putative divalent metal sites and an N-terminal regulatory domain.,HsT19550

ID gène: 5151

UniProt: O60658

Pathways: cAMP Metabolic Process