SPAG6 anticorps (AA 233-290) (AbBy Fluor® 488)
Aperçu rapide pour SPAG6 anticorps (AA 233-290) (AbBy Fluor® 488) (ABIN1695934)
Antigène
Voir toutes SPAG6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 233-290
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Réactivité croisée
- Souris
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Homologie
- Human,Rat,Dog,Cow,Pig,Horse
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human SPAG6
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Isotype
- IgG
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Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- SPAG6 (Sperm Associated Antigen 6 (SPAG6))
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Autre désignation
- SPAG6
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Sujet
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Synonyms: PF16, PF16 protein homolog, Protein PF16 homolog, Repro SA 1, Repro-SA-1, SPAG6, SPAG6_HUMAN, Sperm associated antigen 6, Sperm flagellar protein, Sperm-associated antigen 6.
Background: The correlation of anti-sperm with cases of unexplained infertility implicates a role for these in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].
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ID gène
- 9576
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UniProt
- O75602
Antigène
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