DRAXIN anticorps (AA 251-349) (Biotin)

N° du produit ABIN1700792

L’anticorps Lapin Polyclonal anti-DRAXIN a été validé pour WB, ELISA, IHC (p) et IHC (fro). Il convient pour détecter DRAXIN dans des échantillons de Humain.

Aperçu rapide pour DRAXIN anticorps (AA 251-349) (Biotin) (ABIN1700792)

Antigène: DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DRAXIN est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-DRAXIN anticorps (Biotin)

Épitope: AA 251-349

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human C1orf187

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur DRAXIN

Antigène: DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))

Autre désignation: C1orf187

Sujet:

Synonyms: AGPA3119, C1orf187, Chromosome 1 open reading frame 187, Dorsal inhibitory axon guidance protein, Dorsal repulsive axon guidance protein, DRAXI_HUMAN, Draxin, FLJ34999, MGC117222, Neucrin, OTTHUMP00000002262, UNQ3119.

Background: C1orf187, also known as Draxin, Dorsal repulsive axon guidance protein and Neucrin, is a 349 amino acid secreted protein that is required of the development of the spinal cord and forebrain commissures. C1orf187 acts as a chemorepulsive guidance protein and directs commissural axons during development by repelling neurite outgrowth from the spinal cord. During development, C1orf187 modulates neural crest migration by reducing the polarization of these cells, leading to reduced velocity of migration and increased frequency of changing direction, leading to a net decrease in migrational distance. It acts as an antagonist of the Wnt signaling pathway by inhibiting the stabilization of cytosolic _-catenin via its interaction with LRP6. C1orf187 inhibits outgrowth from the olfactory bulb and likely contributes to the formation of the lateral olfactory tract.

ID gène: 374946