FOXRED1 anticorps (AA 251-350) (Biotin)

N° du produit ABIN1701114

Cet anticorps anti-FOXRED1 est un anticorps Lapin Polyclonal détectant FOXRED1 dans WB, ELISA, IHC (p) et IHC (fro). Adapté pour Souris et Rat.

Aperçu rapide pour FOXRED1 anticorps (AA 251-350) (Biotin) (ABIN1701114)

Antigène: FOXRED1 (FAD-Dependent Oxidoreductase Domain Containing 1 (FOXRED1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXRED1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-FOXRED1 anticorps (Biotin)

Épitope: AA 251-350

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FOXRED1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur FOXRED1

Antigène: FOXRED1 (FAD-Dependent Oxidoreductase Domain Containing 1 (FOXRED1))

Autre désignation: FOXRED1

Sujet:

Synonyms: FAD dependent oxidoreductase domain containing 1, FAD dependent oxidoreductase domain containing protein 1, FAD-dependent oxidoreductase domain-containing protein 1, FOXRED 1, FOXRED1, FP634, FXRD1_HUMAN, H17.

Background: FOXRED1 is a 486 amino acid single-pass membrane protein. Utilizing FAD as a cofactor, FOXRED1 may act as a chaperone protein essential for the function of mitochondrial complex I. Mutations to FOXRED1 may result in mitochondrial complex I deficiency (MT-C1D), which results in a wide range of clinical maladies from lethal neonatal disease to adult onset neurodegenerative disorders. Common phenotypes of MT-C1D include cardiomyopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease. FOXRED1 exists as three alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 11q24.2. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4 % of human genomic DNA and is considered a gene and disease association dense chromosome.

ID gène: 55572