PRICKLE1 anticorps (AA 551-650) (Biotin)

N° du produit ABIN1701363

Cet anticorps anti-PRICKLE1 est un anticorps Lapin Polyclonal détectant PRICKLE1 dans ELISA, IHC (fro) et IHC (p). Adapté pour Rat.

Aperçu rapide pour PRICKLE1 anticorps (AA 551-650) (Biotin) (ABIN1701363)

Antigène: PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRICKLE1 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PRICKLE1 anticorps (Biotin)

Épitope: AA 551-650

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Prickle

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur PRICKLE1

Antigène: PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))

Autre désignation: Prickle

Sujet:

Synonyms: FLJ31627, FLJ31937, MGC138902, MGC138903, EPM1B, Prickle 1, Prickle homolog 1 Drosophila, Prickle like protein 1, Prickle-like 1, Prickle1, REST-Interacting LIM Domain Protein, REST/NRSF interacting LIM domain protein 1, RILP, PRIC1_HUMAN.

Background: Prickle1 is an 831 amino acid protein that contains one PET domain and three LIM zinc-binding domains and localizes to the cytoplasm, as well as to the nuclear membrane. Expressed at higher levels in placenta and at lower levels in liver, brain, kidney, lung and pancreas, Prickle1 is thought to function as a nuclear receptor that interacts with NRSF, a silencer protein that binds the DNA sequence element NRSE (neuron-restrictive silencer element). Defects in the gene encoding Prickle1 are associated with autosomal recessive progressive myoclonic epilepsy-1B, which is characterized by quick jerks of the arms, shoulders or legs. The gene encoding Prickle1 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5 % of the human genome.

ID gène: 144165

Pathways: Signalisation WNT, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development, Protein targeting to Nucleus