RGS14 anticorps (AA 151-250) (Cy3)

N° du produit ABIN1701881

L’anticorps Lapin Polyclonal anti-RGS14 a été validé pour WB, IF (cc) et IF (p). Il convient pour détecter RGS14 dans des échantillons de Souris et Rat.

Aperçu rapide pour RGS14 anticorps (AA 151-250) (Cy3) (ABIN1701881)

Antigène: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RGS14 est conjugé à/à la Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-RGS14 anticorps (Cy3)

Épitope: AA 151-250

Réactivité croisée: Souris, Rat

Homologie: Human,Cow

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RGS14

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur RGS14

Antigène: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Autre désignation: Rgs14

Sujet:

Synonyms: Highly similar to rap1/rap2 interacting protein, OTTHUMP00000223586, OTTHUMP00000223587, Regulation of G protein signaling 14, Regulator of G protein signaling 14, Regulator of G protein signalling 14, Regulator of G-protein signaling 14, RGS 14, RGS14, RGS14_HUMAN.

Background: RGS14 is a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

ID gène: 10636

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling