HDAC4 anticorps (pSer246) (Cy3)

N° du produit ABIN1701941

L’anticorps anti-HDAC4 Polyclonal Lapin est utilisé pour la détection de HDAC4 dans des échantillons de Humain. Il a été validé pour WB et IF.

Aperçu rapide pour HDAC4 anticorps (pSer246) (Cy3) (ABIN1701941)

Antigène: HDAC4 (Histone Deacetylase 4 (HDAC4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC4 est conjugé à/à la Cy3

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-HDAC4 anticorps (Cy3)

Épitope: pSer246

Fonction: Phospho-HDAC4 (Ser246) Polyclonal Antibody, Cy3 Conjugated

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human HDAC4 around the phosphorylation site of Ser246

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000), IF(1:50-200)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur HDAC4

Antigène: HDAC4 (Histone Deacetylase 4 (HDAC4))

Autre désignation: HDAC4

Sujet:

Synonyms: HDAC4Ser246, HDAC4S246, p-HDAC4Ser246, p-HDAC4S246, HD 4, HD4, HDAC 4, HDAC A, HDACA, Histone Deacetylase 4, Histone Deacetylase A, KIAA0288, EC 3.5.1.98, HA6116, HDA4_CAEEL, Histone deacetylase 4, CeHDA-7, Histone deacetylase 7.

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].

ID gène: 9759

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process