EEF2K anticorps (pSer359) (Cy5)

N° du produit ABIN1704156

Détail du produit anti-EEF2K anticorps (Cy5)

Antigène: EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))

Épitope: pSer359

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EEF2K est conjugé à/à la Cy5

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Homologie: Human,Mouse,Rat,Dog,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human EEF2k around the phosphorylation site of Ser359

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur EEF2K

Antigène: EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))

Autre désignation: EEF2k (EEF2K Produits)

Synonymes: anticorps HSU93850, anticorps eEF-2K, anticorps C86191, anticorps SMEF2K, anticorps eEF-2 kinase, anticorps cb365, anticorps fa04b08, anticorps wu:fa04b08, anticorps zgc:100973, anticorps eukaryotic elongation factor 2 kinase, anticorps eukaryotic elongation factor-2 kinase, anticorps EEF2K, anticorps Eef2k, anticorps eef2k, anticorps LOC101930123

Sujet:

Synonyms: EEF2K phospho S359, p-EEF2K phospho S359, Calcium/calmodulin dependent eukaryotic elongation factor 2, Calcium/calmodulin dependent eukaryotic elongation factor 2 kinase, Calmodulin dependent protein kinase III, cb365, eEF 2 kinase, eEF 2K, EEF2K protein, Elongation factor 2 kinase, Eukaryotic elongation factor 2 kinase, kinase eEF2K, SMEF2K, EF2K_HUMAN.

Background: Eukaryotic elongation factor 2 kinase (EEF2k) previously known as Ca2+/calmodulin dependent protein kinase III, is an abundant cytoplasmic protein highly specific for elongation factor 2 (eEf2). Phosphorylation of eEF2 by eEF2 kinase on specific threonine residues results in the inactivation of eEF-2 and in termination of mRNA translation. The activity of eEF2 kinase is not only dependent upon Ca2+ ions, calmodulin (CaM) and insulin, but is also regulated both negatively and positively via phosphorylation by different protein kinases (AMPK, S6K1, p90 RSK). There is also evidence that eEF-2 phosphorylation is involved in the regulation of cell cycle progression, cellular differentiation, oogensis and malignant tumors.

ID gène: 29904

Pathways: AMPK Signaling