alpha Adducin anticorps (pSer436) (Cy5)

N° du produit ABIN1704199

Cet anticorps Lapin Polyclonal détecte spécifiquement alpha Adducin dans WB, IF (cc) et IF (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour alpha Adducin anticorps (pSer436) (Cy5) (ABIN1704199)

Antigène: alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp alpha Adducin est conjugé à/à la Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-alpha Adducin anticorps (Cy5)

Épitope: pSer436

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human alpha Adducin around the phosphorylation site of Ser436

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur alpha Adducin

Antigène: alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

Autre désignation: alpha Adducin

Sujet:

Synonyms: alpha Adducinphospho S436, alpha Adducinphospho Ser436, p-alpha AdducinS436, p-alpha AdducinSer436, ADD 1, ADD A, ADD1, ADD1 protein, ADDA, ADDA_HUMAN, Adducin 1 alpha, Adducin 1 alpha, Alpha adducin, Alpha-adducin, Erythrocyte adducin alpha subunit, Erythrocyte hosphor subunit alpha, Erythrocyte adducin subunit alpha.

Background: Adducins are a family of cytoskeleton proteins encoded by three genes (Alpha, Beta, Gamma). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-actin junction of the membrane skeleton. The cortical actin cytoskeletal network is lost during apoptosis and Adducins are central in the cortical actin network organization. Adducin Alpha is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin Alpha and Adducin Gamma is ubiquitous in contrast to the restricted expression of Adducin Beta. Adducin Beta is expressed at high levels in brain and hematopoietic tissues, such as bone marrow, in humans, and in spleen in mice.

ID gène: 118

Pathways: Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling