Sp3 anticorps (AA 651-750) (Cy7)

N° du produit ABIN1707901

Cet anticorps Lapin Polyclonal détecte spécifiquement Sp3 dans WB, IF (cc) et IF (p). Il présente une réactivité envers Humain.

Aperçu rapide pour Sp3 anticorps (AA 651-750) (Cy7) (ABIN1707901)

Antigène: Sp3 (Sp3 Transcription Factor (Sp3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Sp3 est conjugé à/à la Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-Sp3 anticorps (Cy7)

Épitope: AA 651-750

Homologie: Human,Mouse,Rat,Cow,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SP3

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Sp3

Antigène: Sp3 (Sp3 Transcription Factor (Sp3))

Autre désignation: SP3

Sujet:

Synonyms: D130027J01Rik, DKFZp686O1631, GC binding transcription factor Sp 3, GC binding transcription factor Sp3, MGC105187, OTTMUSP00000014207, SP 3, Sp 3 transcription factor, SP3, Sp3 transcription factor, SP3_HUMAN, Specicity protein 3, SPR 2, SPR-2, SPR2, Transcription factor SP 3, Transcription factor SP3, Transcription factor Sp3.

Background: The Sp transcription factor family includes Sp1, Sp2, Sp3 (SPR-2) and Sp4 (SPR-1). Sp transcription factors share similar structures but do not share simi-lar functions. All four proteins contain a highly conserved DNA-binding domain composed of three zinc fingers at the C-terminus. Sp family members bind the consensus sequence GGGGCGGGGC and other closely related sequences which are known as GC boxes. Sp1, Sp3 and Sp4 share a high affinity for GC boxes while Sp2 does not. Sp2 only weakly binds to GT boxes. Sp1, Sp2 and Sp3 are ubiquitously expressed, while Sp4 is abundantly expressed in brain with limited expression in other tissues. Sp1 and Sp3, but not Sp2 or Sp4, interact with E2, a regulatory element for the 4 subunit of neuronal nicotinic acetylcholine receptors. Sp3 is the only Sp member to inhibit Sp1 and Sp4 media