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PRAM1 anticorps (AA 551-650) (FITC)

PRAM1 Reactivité: Humain IF (cc), IF (p) Hôte: Lapin Polyclonal FITC
N° du produit ABIN1709586
  • Antigène Voir toutes PRAM1 Anticorps
    PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))
    Épitope
    • 14
    • 2
    • 1
    • 1
    AA 551-650
    Reactivité
    • 19
    • 1
    Humain
    Hôte
    • 17
    • 1
    • 1
    Lapin
    Clonalité
    • 19
    Polyclonal
    Conjugué
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PRAM1 est conjugé à/à la FITC
    Application
    • 12
    • 12
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human PRAM1
    Isotype
    IgG
    Top Product
    Discover our top product PRAM1 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))
    Autre désignation
    PRAM1 (PRAM1 Produits)
    Synonymes
    anticorps PRAM1, anticorps AY665714, anticorps PML-RAR, anticorps PRAM-1, anticorps RGD1564330, anticorps PML-RARA regulated adaptor molecule 1, anticorps PML-RAR alpha-regulated adaptor molecule 1, anticorps PRAM1, anticorps Pram1
    Sujet

    Synonyms: PML RAR, PML RARA regulated adaptor molecule 1, PML RARA target gene encoding an Adaptor Molecule 1, PML-RARA-regulated adapter molecule 1, PRAM 1, PRAM, PRAM-1, PRAM_HUMAN, PRAM1.

    Background: Complete remission of acute promyelocytic leukemia can be achieved by treating patients with retinoic acid, and PML-RAR-a (promyelocytic leukemia-retinoic acid receptor alpha fusion protein) plays a major role in mediating retinoic acid effects in leukemia cells. The retinoic acid-induced gene, PRAM-1 (PML-RAR-a target gene encoding an adaptor molecule 1) encodes an adaptor protein which is expressed and modulated during normal human myelopoiesis. PRAM-1 expression is hindered by expression of PML-RAR-a. The 718 amino acid PRAM-1 protein contains eight N-terminal proline-rich repeats and several proline residues that are clustered as type I or type II SH3 recognition motifs. PRAM-1 demonstrates expression in hematopoietic tissues and lung.

    Pathways
    Regulation of Leukocyte Mediated Immunity
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