CPA3 anticorps (AA 101-200) (HRP)

N° du produit ABIN1711267

Cet anticorps Lapin Polyclonal détecte spécifiquement CPA3 dans WB, ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Rat.

Aperçu rapide pour CPA3 anticorps (AA 101-200) (HRP) (ABIN1711267)

Antigène: CPA3 (Carboxypeptidase A3 (Mast Cell) (CPA3))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CPA3 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-CPA3 anticorps (HRP)

Épitope: AA 101-200

Réactivité croisée: Rat

Homologie: Human,Mouse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CPA3/MC-CPA

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CPA3

Antigène: CPA3 (Carboxypeptidase A3 (Mast Cell) (CPA3))

Autre désignation: CPA3/MC-CPA

Sujet:

Synonyms: carboxypeptidase A, Carboxypeptidase A3, carboxypeptidase A3 mast cell, CBPA3_HUMAN, Cpa3, Mast cell carboxypeptidase A, mast cell carboxypeptidase A3, MC CPA, MC-CPA.

Background: Carboxypeptidase A (CPA) is a pancreatic exopeptidase which hydrolyses the peptide bond adjacent to the C-terminal end in polypeptide chains. Mast cell carboxypeptidase A (MC-CPA), a part of the peptidase M14 family, is a highly conserved metalloprotease localized to the secretory granules, along with trytases and chymases. MC-CPA is stored as an active enzyme in the granule and is released, along with other inflammatory mediators, upon mast cell degranulation. MC-CPA mirrors pancreatic carboxypeptidase A in cleaving COOH-terminal aromatic and aliphatic amino acid residues. The optimum pH of MC-CPA is between neutral and basic, depending upon the substrate. The MC-CPA gene, CPA3, resides on chromosome 3 and contains 11 exons.

ID gène: 1359

Pathways: Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones