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POLM anticorps (AA 261-360) (HRP)

POLM Reactivité: Humain WB, IHC (fro), IHC (p) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1711280
  • Antigène Voir toutes POLM Anticorps
    POLM (Polymerase (DNA Directed), mu (POLM))
    Épitope
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 261-360
    Reactivité
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 22
    Lapin
    Clonalité
    • 22
    Polyclonal
    Conjugué
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp POLM est conjugé à/à la HRP
    Application
    • 13
    • 13
    • 9
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Mouse,Rat,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human DNA polymerase mu
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C/-80 °C
    Stockage commentaire
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Date de péremption
    12 months
  • Antigène
    POLM (Polymerase (DNA Directed), mu (POLM))
    Autre désignation
    DNA polymerase mu (POLM Produits)
    Synonymes
    anticorps polmu, anticorps zgc:56122, anticorps POLM, anticorps Pol Mu, anticorps Tdt-N, anticorps AI462166, anticorps B230309I03Rik, anticorps polymerase (DNA directed), mu, anticorps DNA polymerase mu, anticorps polm, anticorps POLM, anticorps CC1G_09351, anticorps VDBG_09335, anticorps Polm
    Sujet

    DNA polymerase mu shares a number of characteristics with DNA polymerase Beta as well as with terminal deoxynucleotideyltransferase. Pol mu purportedly plays a role in microhomology mediated joining and the repair of double-stranded breaks. However, unlike other DNA polymerases, which show substrate specificity for deoxynucleotides, DNA Pol mu incorporates both deoxynucleotides and ribonucleotides in a template- directed manner. This unusual capability implies a novel role for this polymerase in DNA repair.

    Subcellular location: Nucleus

    Synonyms: DNA Polymerase Mu, DNA-directed DNA polymerase mu, DNA-directed DNA/RNA polymerase mu, DPOLM_HUMAN, FLJ35482, Pol iota, Pol Mu, Polm, POLM protein, Polymerase DNA directed mu, Polymerase DNA directed mu, Tdt N, Tdt-N, TdtN, Terminal transferase.

    ID gène
    27434
    Pathways
    Réparation de l'ADN, Production of Molecular Mediator of Immune Response
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