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DZIP1 anticorps (AA 21-120) (HRP)

DZIP1 Reactivité: Rat WB, IHC (p), IHC (fro) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1711288
  • Antigène Voir toutes DZIP1 Anticorps
    DZIP1 (DAZ Interacting Protein 1 (DZIP1))
    Épitope
    • 14
    • 8
    • 2
    • 2
    • 2
    • 1
    AA 21-120
    Reactivité
    • 25
    • 14
    • 2
    Rat
    Hôte
    • 36
    • 3
    Lapin
    Clonalité
    • 39
    Polyclonal
    Conjugué
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DZIP1 est conjugé à/à la HRP
    Application
    • 19
    • 13
    • 13
    • 12
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Dog,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human DZIP1
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C/-80 °C
    Stockage commentaire
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Date de péremption
    12 months
  • Antigène
    DZIP1 (DAZ Interacting Protein 1 (DZIP1))
    Autre désignation
    DZIP1 (DZIP1 Produits)
    Synonymes
    anticorps dzip, anticorps dzipt1, anticorps DZIP1, anticorps MGC142440, anticorps MGC146244, anticorps rp11-23e3.3, anticorps 2510025K24Rik, anticorps 2810422M04Rik, anticorps mKIAA0996, anticorps DZIP, anticorps DZIPt1, anticorps igu, anticorps igu/dzip1, anticorps si:dz52i16.1, anticorps DAZ interacting zinc finger protein 1, anticorps DAZ interacting zinc finger protein 1 L homeolog, anticorps DAZ interacting protein 1, anticorps DZIP1, anticorps dzip1.L, anticorps dzip1, anticorps Dzip1
    Sujet

    DZIP1 (DAZ interacting protein 1) is also known as DZIP or DZIP2 and is a 867 amino acid protein which is expressed as three isoforms, designated DZIPb, DZIPt1 and DZIPt2. DZIP1 is localized to testis, oocytes, ovary and fetal brain, as well as in embryonic stem cells and germ cells. In testis, DZIP1 is localized to the nucleus and also shows some cytoplasmic distribution in spermatogonia. DZIP1 belongs to the C2H2-type zinc-finger protein family, and, characteristc of the C2H2-type zinc-finger protein family, DZIP1 contains one C2H2-type zinc-finger region through which it is thought to interact with DAZ, an interaction that promotes spermiogenesis. DZIP1 expression is not found in those afflicted with Sertoli cell-only syndrome (characterized by the absence of germ cells in the testis), suggesting that the lack of DZIP1 may be involved in the pathogenesis of Sertoli cell-only syndrome-induced male sterility.

    Subcellular location: Cytoplasm, Nucleus

    Synonyms: DAZ interacting protein 1/2, DAZ interacting protein testis1, DZIP, DZIP2, DZIPt1, Zinc finger DAZ interacting protein 1, Zinc finger protein DZIP1, Zinc finger protein DZIPt1.

    Pathways
    Signalisation Hedgehog, Protein targeting to Nucleus
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