DUSP10 anticorps (AA 161-260) (HRP)

N° du produit ABIN1711662

Cet anticorps anti-DUSP10 est un anticorps Lapin Polyclonal détectant DUSP10 dans WB, ELISA, IHC (p) et IHC (fro). Adapté pour Humain et Souris.

Aperçu rapide pour DUSP10 anticorps (AA 161-260) (HRP) (ABIN1711662)

Antigène: DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP10 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-DUSP10 anticorps (HRP)

Épitope: AA 161-260

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DUSP10/MKP5

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur DUSP10

Antigène: DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))

Autre désignation: DUSP10/MKP5

Sujet:

Synonyms: Dual specicity phosphatase 10, Dual specicity phosphatase MKP 5, Dual specicity phosphatase MKP5, Dual specicity protein phosphatase 10, DUS10_HUMAN, DUSP 10, DUSP10, DUSP10 protein, MAP kinase phosphatase 5, Mitogen activated protein kinase phosphatase 5, Mitogen-activated protein kinase phosphatase 5, MKP 5, MKP-5, MKP5, Serine/threonine specic protein phosphatase.

Background: Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. MKP-5 preferentially binds to p38, but also to SAPK/JNK. It is ubiquitously expressed and localizes to both the cytoplasm and the nucleus. MKP-5 has been implicated in cell proliferation and apoptosis, tumor invasion and immune responses.

ID gène: 11221