Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

GC-Rich Promoter Binding Protein 1 (GPBP1) (AA 11-110) anticorps (HRP)

GPBP1 Reactivité: Souris WB, IHC (p), IHC (fro) Hôte: Lapin Polyclonal HRP
N° du produit ABIN1711707
  • Antigène Voir toutes GC-Rich Promoter Binding Protein 1 (GPBP1) Anticorps
    GC-Rich Promoter Binding Protein 1 (GPBP1)
    Épitope
    • 14
    • 3
    • 1
    • 1
    AA 11-110
    Reactivité
    • 18
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 22
    Lapin
    Clonalité
    • 22
    Polyclonal
    Conjugué
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    HRP
    Application
    • 13
    • 13
    • 9
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human GPBP1/Vasculin
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Stock
    -20 °C/-80 °C
    Stockage commentaire
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Date de péremption
    12 months
  • Antigène
    GC-Rich Promoter Binding Protein 1 (GPBP1)
    Autre désignation
    GPBP1/Vasculin (GPBP1 Produits)
    Synonymes
    anticorps MGC80437, anticorps Vasculin, anticorps DKFZp459A203, anticorps GPBP, anticorps SSH6, anticorps VASCULIN, anticorps 1700034P14Rik, anticorps AU019836, anticorps D230035M11Rik, anticorps Gpbp, anticorps mGPBP, anticorps RGD1305492, anticorps GC-rich promoter binding protein 1 L homeolog, anticorps GC-rich promoter binding protein 1, anticorps gpbp1.L, anticorps gpbp1, anticorps GPBP1, anticorps Gpbp1
    Sujet

    Vascular wall-linked protein, or Vasculin, is primarily expressed in the arterial wall and in plasma. It is also differentially expressed in human atherogenesis. Alternative splicing of exon 3 of the Vasculin gene produces three variants. Vasculin binds to and activates the minimal self-sufficient promoter element (MSPE) of the mouse Ada gene promoter and binds to and partially suppresses the GC-rich promoter of the nonhomologous human TOP2A gene promoter. It acts as a nuclear factor that can form complexes with TATA-binding proteins, transcription factors TFIIB and TFIIF, RNA polymerase II and p300. The regulated expression of Vasculin in plaques suggests that it may be involved in atherogenesis, and its presence in plasma may implicate Vasculin as a marker for atherosclerosis.

    Subcellular location: Cytoplasm, Nucleus

    Synonyms: DKFZp761C169, GC rich promoter binding protein 1, GC-rich promoter-binding protein 1, GPBP, Gpbp1, GPBP1_HUMAN, MGC126339, SSH6, Vascular wall linked, Vascular wall-linked protein, Vasculin.

    ID gène
    65056
Vous êtes ici:
Support technique