PA2G4 anticorps (AA 201-320) (HRP)

N° du produit ABIN1711818

Cet anticorps anti-PA2G4 est un anticorps Lapin Polyclonal détectant PA2G4 dans WB, ELISA, IHC (p) et IHC (fro). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour PA2G4 anticorps (AA 201-320) (HRP) (ABIN1711818)

Antigène: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PA2G4 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-PA2G4 anticorps (HRP)

Épitope: AA 201-320

Réactivité croisée: Humain, Souris, Rat

Homologie: Cow,Sheep,Pig,Chicken,Rabbit,Zebrafish

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human EBP1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PA2G4

Antigène: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Autre désignation: EBP1

Sujet:

Synonyms: AA672939, Cell cycle protein p38 2G4 homolog, Cell cycle protein p38-2G4 homolog, ErbB-3 binding protein 1, ErbB3 binding protein 1, ErbB3-binding protein 1, ErbB3-binding protein Ebp1, hG4 1, hG4-1, IRES-specic cellular trans-acting factor 45 kDa, MGC81621, MGC94070, Mpp1, p38 2G4, PA2G4, PA2G4_HUMAN, Plfap, proliferation associated 2G4, proliferation associated 2G4, 38-KD, proliferation-associated 2G4, 38 kDa, proliferation-associated 2G4, a, proliferation-associated protein 1, proliferation-associated protein 2G4, Protein p38-2G4, si:dz150i12.2, wu:fb19b11, wu:ft56d05, zgc:86732.

Background: EBP1 is a member of the peptidase M24C family and functions as an RNA-binding protein involved in cellular proliferation and differentiation processes. It is expressed in a variety of cell lines, including a wide range of tumor cell lines, and localizes to the cytoplasm. Upon treatment with Neuregulin-1 (heregulin), EBP1 translocates to the nucleus. EBP1 is a component of pre-ribosomal ribonucleoprotein complexes, participating in ribosome assembly and regulating the later steps of rRNA processing. In addition, EBP1 interacts with ErbB-3 and may function as a modulator of the ErbB-3-mediated signal transduction pathway by regulating the effects of Neuregulin-1 (heregulin). EBP1 also associates with histone deacetylases (HDACs), functioning as a transcriptional co-repressor of cell cycle regulatory genes.

ID gène: 5036

Pathways: Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Toll-Like Receptors Cascades