GPR124 anticorps (PE)
Aperçu rapide pour GPR124 anticorps (PE) (ABIN1712768)
Antigène
Voir toutes GPR124 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human G protein coupled receptor 124
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Isotype
- IgG
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Commentaires
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Exitation/Emission: 480,565nm/578nm
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at 4°C
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Date de péremption
- 12 months
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- GPR124 (G Protein-Coupled Receptor 124 (GPR124))
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Autre désignation
- Gpr124/Tem5
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Sujet
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Tumor endothelial markers (TEMs) are abundantly expressed in the blood vessels of human solid tumors during angiogenesis and neoangiogensis. These include TEM1 (endosialin), TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1). TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues. TEM5 is a seven-pass transmembrane receptor, whereas TEM1, TEM7 and TEM8 span the membrane once. TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis. TEM7 is highly expressed in tumor endothelium and neurons. Therefore, TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies.
Subcellular location: Extracellular
Synonyms: DKFZp434C211, DKFZp434J0911, FLJ14390, G protein coupled receptor 124, G-protein coupled receptor 124, GP124_HUMAN, GPR 124, GPR124, KIAA1531, TEM 5, TEM5, Tumor endothelial marker 5, Tumor endothelial marker 5 precursor, GPCR GPR124. -
ID gène
- 25960
Antigène
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