FZD6 anticorps (AA 11-110)

N° du produit ABIN1713791

L’anticorps anti-FZD6 Polyclonal Lapin est utilisé pour la détection de FZD6 dans des échantillons de Humain. Il a été validé pour WB, IHC (p), IF (cc), IF (p) et IHC (fro).

Aperçu rapide pour FZD6 anticorps (AA 11-110) (ABIN1713791)

Antigène: FZD6 (Frizzled Family Receptor 6 (FZD6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FZD6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-FZD6 anticorps

Épitope: AA 11-110

Fonction: Frizzled 6 Polyclonal Antibody

Réactivité croisée: Rat

Homologie: Human,Mouse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Frizzled 6

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000),

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur FZD6

Antigène: FZD6 (Frizzled Family Receptor 6 (FZD6))

Autre désignation: Frizzled 6

Sujet:

Synonyms: FZ6, FZ-6, HFZ6, NDNC10, Frizzled-6, FZD6

Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

ID gène: 8323

UniProt: O60353

Pathways: Signalisation WNT, Tube Formation