DMAP1 anticorps (AA 31-130)

N° du produit ABIN1714047

Cet anticorps anti-DMAP1 est un anticorps Lapin Polyclonal détectant DMAP1 dans ELISA, IHC (p), ICC, IF (cc), IF (p) et IHC (fro). Adapté pour Xenopus laevis.

Aperçu rapide pour DMAP1 anticorps (AA 31-130) (ABIN1714047)

Antigène: DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Reactivité: Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DMAP1 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-DMAP1 anticorps

Épitope: AA 31-130

Réactivité croisée: Xenopus laevis

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DMAP1

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur DMAP1

Antigène: DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Autre désignation: DMAP1

Sujet:

Synonyms: DKFZp686L09142, DMAP 1, DNA methyltransferase 1-associated protein 1, DNMAP 1, DNMAP1, DNMT1-associated protein 1, DNMT1-associated protein 1, DNMTAP 1, DNMTAP1, EAF 2, EAF2, FLJ11543, KIAA1425, MAT 1-mediated transcriptional repressor, MGC55593, SWC 4, SWC4, zgc:55593.

Background: Methylation of DNA contributes to the regulation of gene transcription in eukaryotic systems. DNA methylation is predominantly found on cytosine residues that are present in dinucleotide motifs consisting of a 5' cytosine followed by a guanosine (CpG), and it requires the enzymatic activity of DNA methyltransferases (DNMTs), which results in transcriptional repression of the methylated gene. DNA methyltransferase 1-associating protein (Dmap1) binds to methyl-CpG rich domains and mediate the transcriptional inhibition associated with DNA methylation. Dmap1 interacts with Daxx to enhanced Daxx-mediated repression of glucocorticoid receptor transcriptional activity. Daxx also protects Dmap1 from protein degradation in vivo.

ID gène: 55929