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PBX1 anticorps (AA 221-340)

PBX1 Reactivité: Humain WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1714066
  • Antigène Voir toutes PBX1 Anticorps
    PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))
    Épitope
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 221-340
    Reactivité
    • 23
    • 7
    • 7
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 15
    • 7
    • 1
    Lapin
    Clonalité
    • 17
    • 6
    Polyclonal
    Conjugué
    • 19
    • 2
    • 1
    • 1
    Cet anticorp PBX1 est non-conjugé
    Application
    • 17
    • 13
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit,Zebrafish
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human PBX1
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))
    Autre désignation
    PBX1 (PBX1 Produits)
    Synonymes
    anticorps fi29e01, anticorps pbx1b, anticorps wu:fi29e01, anticorps zgc:55265, anticorps 2310056B04Rik, anticorps AI848790, anticorps AU015730, anticorps D230003C07Rik, anticorps Pbx-1, anticorps Pbx1a, anticorps Pbx1b, anticorps PBX1A, anticorps Xpbx1, anticorps Xpbx1b, anticorps PBX homeobox 1, anticorps pre-B-cell leukemia homeobox 1a, anticorps pre B cell leukemia homeobox 1, anticorps pre-B-cell leukemia homeobox 1 S homeolog, anticorps PBX1, anticorps pbx1a, anticorps Pbx1, anticorps pbx1.S
    Sujet

    Pbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1,19)(q23,p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92 % and 94 % respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.

    Subcellular location: Nucleus

    Synonyms: DKFZp686B09108, Homeo box protein PBX1, Homeo box protein PRL, Homeobox protein PBX 1, Homeobox protein PBX1, Homeobox protein PRL, MGC126627, PBX 1, Pbx1, PBX1_HUMAN, Pre B cell leukemia homeobox 1, Pre B cell leukemia transcription factor 1, Pre-B-cell leukemia transcription factor 1, PRL.

    ID gène
    5087
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