DUSP10 anticorps (AA 161-260)

N° du produit ABIN1714147

Cet anticorps Lapin Polyclonal détecte spécifiquement DUSP10 dans WB, IF (cc), IF (p), IHC (p) et IHC (fro). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour DUSP10 anticorps (AA 161-260) (ABIN1714147)

Antigène: DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP10 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-DUSP10 anticorps

Épitope: AA 161-260

Fonction: DUSP10 Polyclonal Antibody

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DUSP10/MKP5

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000),

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur DUSP10

Antigène: DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))

Autre désignation: DUSP10/MKP5

Sujet:

Synonyms: Dual specicity phosphatase 10, Dual specicity phosphatase MKP 5, Dual specicity phosphatase MKP5, Dual specicity protein phosphatase 10, DUS10_HUMAN, DUSP 10, DUSP10, DUSP10 protein, MAP kinase phosphatase 5, Mitogen activated protein kinase phosphatase 5, Mitogen-activated protein kinase phosphatase 5, MKP 5, MKP-5, MKP5, Serine/threonine specic protein phosphatase.

Background: Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. MKP-5 preferentially binds to p38, but also to SAPK/JNK. It is ubiquitously expressed and localizes to both the cytoplasm and the nucleus. MKP-5 has been implicated in cell proliferation and apoptosis, tumor invasion and immune responses.

ID gène: 11221